Agilent 6140A Single Quadrupole Mass Spectrometer w/ 1200 UPLC
Mass Range
10 to 1350 m/z
Mass Accuracy
± 0.13 u
Scan Speed
10,000 u/s in fast mode and 2500 u/s in normal mode
- Delivers unmatched analytical performance for routine QC and research applications
- Ultra-fast scanning for high-throughput and fast chromatography applications
- Simplifies sample preparation and LC method development with exceptional sensitivity
- Features ultrafast ion polarity switching for maximum information from a single injection
- Orthogonal pneumatic nebulizer reduces chemical noise across diverse LC conditions
- High-capacity solvent drying system supports thermally-sensitive compound analysis
- Platinum-plated dielectric capillary enhances sensitivity and optimizes in-source fragmentation
- Multisignal acquisition supports up to four modes, including polarity switching and SIM/scan
- User-friendly operation through Agilent ChemStation Workstation Software
The Agilent 6140A Single Quadrupole Mass Spectrometer w/ 1200 UPLC delivers unmatched analytical performance and proven day-after-day reliability from routine QC to research applications. This 6140A model brings maximum performance plus ultra-fast scanning for fast chromatography and high-throughput applications. This system allows users to rapidly screen compounds and confirm molecular weights, purify target compounds in complex mixtures, quantitate target compounds, positively identify impurities and more. The Agilent 6140A Single Quadrupole Mass Spectrometer provides unmatched sensitivity, simplifying sample preparation and LC method development. An ultrafast scan speed allows users to take full advantage of UPLC separations, as well as featuring ultrafast ion polarity switching to return maximum information from a single injection, even with narrow LC peaks. The Agilent 6140A Single Quadrupole Mass Spectrometer w/ 1200 UPLC can be fully controlled from the included Agilent ChemStation Workstation Software, which allows for user-friendly operation in data acquisition, analysis, instrument control, automation, and more.
Additional high-performance design features of the Agilent 6140A Single Quadrupole Mass Spectrometer include:
- Orthogonal pneumatic nebulizer design allows for a wide range of LC conditions by helping to reduce chemical noise.
- High-capacity solvent drying system – reduces chemical noise and permits the analysis of thermally-sensitive compounds through user control of gas flow rate and gas temperature.
- Resistive capillary for fast switching
- Fraction collection capability – can monitor and trigger the collection of fractions based on mass, analog signal input, or time. For mass-based determination, up to 16 m/z values can be monitored. Requires optional I/O Accessory Module.
This turnkey Agilent LC/MS system was recertified and calibrated by a factory trained engineer and is ready to ship on demand. This system comes with everything needed for easy installation and setup. All of our equipment is fully tested to perform at factory specifications before being shipped.
The Agilent 6140A Single Quadrupole Mass Spectrometer w/ 1200 UPLC includes:
- > Agilent 6140A Single Quadrupole Mass Spectrometer
- > Agilent MS40+ Rotary Vane Vacuum Pump
- > G1948B ESI Ionization Source
- > G1312B Binary Pump (G1311A Quaternary Pump available, please inquire)
- > G1329A Autosampler
- > G1330B ALS Thermostat
- > G1316A TCC
- > G1379B Degasser
- > G1315C DAD Detector
- > Windows 11 Professional 64-Bit Data Station with Flatscreen Monitor
- > ChemStation Version 4.3 Software Installed
- > All Power Cords
- > Can/Crossover Cables
- > Agilent Lan Interface Card Built-In
- > Solvent Tubing
- > Capillaries
- > Agilent 4 Peak Test w/ Lab Advisor Diagnostics Report & Mass Spec Tuning Report
- > Full 180 Day Parts and Labor Warranty
G1315C Diode Array Detector Diagnostic Tests:
- Filter Test: The test moves the filter into the light path and measures the relative absorbance in the filter position.
- Dark Current Test: The test measures the dark current from the detector optic.
- Holmium Oxide Test: The test measures the Holmium spectrum from the built-in Holmium filter. The spectrum is evaluated for peaks at different wavelengths.
- Lamp Intensity Test: The test verifies functionality of the UV lamp at various wavelengths.
- Wavelength Intensity Test: The test confirms the accuracy of wavelengths measured.
- Baseline Noise Test: The test measures the amount of baseline noise drift identified by the detector.
- Pressure Test: The pressure test is a quick, built-in test designed to demonstrate the pressure tightness (up to 400 bar) of the system.
- Leak Test: The leak test is a built-in troubleshooting designed to demonstrate the leak-tightness of the pump.
- Thermostat Test: Evaluates the cooling and heating performance of the two Peltier elements.
- Injector Steps: Performs each movement of the sampling sequence under manual control. This is useful for confirming autosampler functionality.
- 4 Peak Test (Isocratic Standard): Standard test published by Agilent to confirm complete functionality of the 1200 LC System.
Agilent 6140A Single Quadrupole Mass Spectrometer Specifications
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Mass Range |
10 – 1350 m/z |
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Mass Accuracy |
± 0.13 u within the calibrated mass range in scan mode |
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Mass Axis Stability |
The mass drift does not exceed the larger absolute value of ± 0.1 Da or ± 100 ppm of measured mass over a 12 hour period at constant temperature ± 3 degrees centrigrade. |
|
Scan Speed |
10,000 u/s in fast mode and 2500 u/s in normal mode |
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SIM Sensitivity |
ESI at 400 μ/min or APCI at 1000 μ/min
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Scan Sensitivity |
ESI at 400 μ/min or APCI at 1000 μ/min
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Flow Rate |
ESI: Up to 1.0 ml/min water without a flow splitter
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Multisignal acquisition |
Ability to cycle through four acquisition modes on a scan-by-scan basis within a single run. Up to four analysis modes can be viewed in the software window and can be linked together to facilitate processing and analysis. Modes of operation: positive/negative polarity switching, variable fragmentor voltage selection, and concurrent SIM/scan. |
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Operating Conditions |
Temperature range: 15 °C to 35 °C (59 °F to 95 °F)
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Dimensions |
Height: 65 cm (26 in)
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Electrical Requirements |
200-240V, 50/60Hz |
| DAD Detector | Specification |
| Detection Type | 1024-element photodiode array |
| Light Source | Deuterium and tungsten lamps |
| Wavelength Range | 190 - 950 nm |
| Short Term Noise (ASTM) Single and Multi-Wavelength | ± 0.8 × 10 -5 AU at 254 and 750 nm |
| Drift | 0.9 × 10 -3 AU/hr at 254 nm |
| Linear Absorbance Range | > 2.0 AU (upper limit) |
| Wavelength Accuracy | ± 1 nm |
| Wavelength Bunching | 1 - 400 nm |
| Slit Width | 1, 2, 4, 8, 16 nm |
| Diode Width | < 1 nm |
| Flow Cells |
Standard: 13 µL volume, 10 mm cell path length and 120 bar (1740 psi) pressure maximum |
| Binary Pump | Specification |
| Hydraulic System | Two dual piston in series pumps with proprietary servo-controlled variable stroke drive, floating piston design and active inlet valve |
| Setable Flow Range | 0.001 – 5 ml/min, in 0.001 ml/min increments |
| Flow Range |
0.1 - 5.0 mL/min |
| Flow Precision | ≤ 0.07% RSD or ≤ 0.02 min SD, whatever is greater |
| Flow Accuracy | ± 1% or 10 µl/min, what ever is greater |
| Pressure Operating Range | Operating range 0 to 600 bar (0 – 7800 psi) up to 5 ml/min |
| Pressure Pulsation | < 2 % amplitude (typically < 1 %), at 1 ml/min isopropanol, at all pressures > 1 MPa |
| Compressibility Compensation | User-selectable, based on mobile phase compressibility |
| Recommended pH Range | 1.0 - 12.5 |
| Gradient Formation | High-pressure binary mixing |
| Delay Volume | 600 to 800 µl, dependent on back pressure |
| Composition Range | 0 to 100% (1 to 99% or 5 µl/min per channel, whatever is greater is recommended) |
| Composition Precision | < 0.15% RSD |
| Composition Accuracy | ± 0.35% absolute |
| Autosampler | Specification |
| Injection Range | 0.1 - 100 µl in 0.1 µl increments |
| Precision |
< 0.25 % RSD of peak areas from 5 to 100 µl < 1 % RSD of peak areas from 1 to 5 µl |
| Pressure Range | Operating range 0 - 60 MPa (0 - 600 bar, 0 - 8850 psi) |
| Sample Viscosity Range | 0.2 to 50 cp |
| Sample Capacity |
100 × 2 mL vials in 1 tray
40 × 2 mL vials in ½ tray 15 × 6 mL vials in ½ tray (Agilent vials only) |
| Injection Cycle Time | 50 s for draw speed 200 µL/min, ejection speed 200 µL/min, injection volume 5 µL |
| Carryover | Typically < 0.1 %, < 0.05 % with external needle cleaning |
| ALS Thermostat | Specification |
| Temperature Range | 4°C to 40°C in 1°C increments |
| Temperature Accuracy at Ambient Temperatures < 25°C and Humidity < 50% | -1°C to +4°C at a setpoint of 4°C |
| Temperature Accuracy at Ambient Temperatures > 25°C and Humidity > 50% | -1°C to +5°C at a setpoint of 4°C |
| Column Compartment | Specification |
| Temperature Range | Ambient -10°C to 80°C at flow rates up to 5 mL/min |
| Temperature Stability | ± 0.15 °C |
| Temperature Accuracy | ± 0.8°C (± 0.5°C with calibration) |
| Column Capacity | Three 30 cm |
| Warm-Up/Cool-Down Time |
5 minutes from ambient to 40°C
10 minutes from 40°C to 20°C |
| Dead Volume |
3 µl left heat exchanger 6 µl right heat exchanger |
| Degasser | Specification |
| Number of Solvent Channels | 4 |
| Maximum Flow Rate | 0 - 10 mL/min per channel |
| Internal Volume Per Channel | Typically 12 ml per channel |
| Materials in Contact with Solvent | PTFE, PEEK |
| pH Range | 1 - 14 |
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Computer Specifications |
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| Processor | Intel Core I5-8500 CPU |
| RAM | 32.0 GB |
| Hard Drive | 500GB Internal SSD |
| Operating System | Windows 11 Professional, 64-bit |
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